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CD8a Mouse anti-Human, Super Bright 436, Clone: RPA-T8, eBioscience™

Mouse Monoclonal Antibody

Marca:  Invitrogen 62-0088-42

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15923344

  • 278.00€ / paquete de 100


Fecha estimada de envío
26-08-2020
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Descripción

Descripción

Please refer to the datasheet for Super Bright Staining Buffer for more information. Excitation: 405 nm; Emission: 436 nm; Laser: Violet Laser Super Bright Polymer Dyes are sold under license from Becton, Dickinson and Company. CD8 (Cluster of Differentiation 8) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediate efficient cell-cell interactions within the immune system. The CD8 antigen acts as a co-receptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer (NK) cells, subpopulations of peripheral blood null cells, thymocytes and bone marrow cells. The CD8 co-receptor functions as either a homodimer composed of two alpha chains, or as a disulfide-linked heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. The majority of CD8+ T cells express CD8 as a alpha/beta heterodimer. In HIV, the HIV-2 envelope glycoprotein binds CD8 alpha chain (but not the beta chain).
Especificaciones

Especificaciones

CD8a
Monoclonal
5 μL/Test
PBS with BSA and 0.09% sodium azide; pH 7.2
P01732
CD8A
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
925
Flow Cytometry
RPA-T8
Super Bright 436
CD8A
Liquid
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
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