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CD7 Mouse anti-Human, Mouse, Clone: 2A4E6, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 60209-2-IG-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16887215

  • 121.38€ / 20 microlitros
Fecha estimada de envío: 30-05-2022
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Descripción

Descripción

CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on maligt B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3′-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Expression of CD7 is an important marker used in leukemia diagnostics.
Especificaciones

Especificaciones

CD7
Monoclonal
1.5 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P09564, P50283
CD7
CD7 Fusion Protein Ag1805
20 μL
Primary
Mouse, Human
Liquid
Immunohistochemistry (Paraffin), Western Blot
2A4E6
Unconjugated
CD7
CD7, CD7 molecule, GP40, LEU 9, T cell antigen CD7, T cell leukemia antigen, T cell surface antigen Leu 9, Tp40, TP41
Mouse
Protein A
RUO
12516, 924
Antibody
IgG1
Videos
SDS
Documentos
Certificados
Ofertas especiales

Ofertas especiales