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CD5 Mouse, anti-Human, APC, Clone: UCHT2, STEMCELL Technologies

Mouse Monoclonal Antibody

Marca:  Stemcell Technologies 60082AZ.1

Detalles adicionales : Peso : 0.00110kg

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Código de producto. 17188921

  • 219.45€ / 25 tests
Fecha estimada de envío: 08-11-2022
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Descripción

Descripción

  • The UCHT2 antibody reacts with CD5, an ∼67 kDa single-chain type I glycoprotein and member of the scavenger receptor superfamily, which is constitutively expressed on thymocytes, T cells, B cell subsets, peripheral blood dendritic cells and some leukemia and lymphoma cells, including chronic B lymphocytic leukemia (B-CLL) cells
  • CD5 is expressed at low levels on thymocytes and at high density on mature T cells
  • Putative ligands include CD5L and CD72
  • CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T cell/B cell interactions via its physical and functional associations with the T cell receptor/CD3 complex and the B cell receptor
  • Studies with CD5 knockout mice indicate that CD5 negatively regulates antigen receptor-mediated signaling in thymocytes and mature T cells
  • The UCHT2 antibody binds to epitope 2 located in the extracellular domain of CD5
Especificaciones

Especificaciones

CD5
Monoclonal
APC
25 Tests
Human, Chimpanzee, Rhesus Monkey, Cynomolgus
T Cells
Immunocytochemistry, Flow Cytometry, Western Blot, Immunohistochemistry
UCHT2
Mouse
Primary
IgG1 κ
Videos
SDS
Documentos
Certificados
Ofertas especiales

Ofertas especiales