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CD49d (Integrin alpha 4) Mouse anti-Human, Super Bright 702, Clone: 9F10, eBioscience™

Mouse Monoclonal Antibody

Marca:  Invitrogen 67-0499-42

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15933734

  • 292.00€ / paquete de 100


Fecha de envío estimada
del proveedor 02-10-2019
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Descripción

Descripción

Light sensitivity: This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (Product No. 00-8222) (100 μL of cell sample + 100 μL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No. 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 405 nm; Emission: 702 nm; Laser: Violet Laser The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains. Alpha4 chain associates with either beta1 or beta7 chain. It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain. These ligands included Madcam, VCAM, and fibronectin. Madcam is known as the principal ligand for integrin alpha4beta7. Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
Especificaciones

Especificaciones

CD49d (Integrin alpha 4)
Monoclonal
5 μL/Test
PBS with BSA and 0.09% sodium azide; pH 7.2
P13612
IA4; ITGA4
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
9F10
Super Bright 702
ITGA4
Liquid
ITGA4
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3676
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