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CD45, TRI-COLOR, clone: HI30, Invitrogen™

Mouse Monoclonal Antibody

327.00€ - 1334.00€

Especificaciones

Antígeno CD45
Clon HI30
Especies diana Human
Conjugado TRI-COLOR
Isotipo IgG1
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
10058202
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Invitrogen
MHCD4506
0.5mL
327.00€
cada uno
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Ahorre hasta 
»
Envío estimado: 22-12-2021
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10119852
Ver documentos Detalles de la promoción
Invitrogen
MHCD45065
2.5mL
1334.00€
cada uno
Ver productos alternativos
Ahorre hasta 
»
Envío estimado: 22-12-2021
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells.

The TRI-COLOR™ conjugate is a tandem R-phycoerythrin (PE)-Cy5™ conjugate that permits simultaneous multicolor labeling and detection of multiple targets with excitation by a single excitation source-the 488 nm line of the argon-ion laser.
Especificaciones

Especificaciones

CD45
Human
IgG1
Monoclonal
Liquid
Antibody
Store at 2 - 8 °C.
HI30
TRI-COLOR
Flow Cytometry
Primary
Monoclonal
PBS with BSA, sucrose and 0.1% sodium azide
ASR, ASR/IVD
SDS
Product Certifications