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CD40 Rat anti-Mouse, FITC, Clone: 3/23, BD

Rat Monoclonal Antibody

233.00€ - 505.00€

Especificaciones

Antígeno CD40
Clon 3/23
Concentración 0.5mg/mL
Aplicaciones Flow Cytometry
Clasificación Monoclonal
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
15801399
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BD Biosciences
561845
0.1 mg
233.00€
cada uno
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Fecha estimada de envío: 14-05-2024
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15827398
Ver documentos Detalles de la promoción
BD Biosciences
553790
0.5 mg
505.00€
cada uno
Ver productos alternativos
Ahorre hasta 
»
Fecha estimada de envío: 14-05-2024
para ver el stock
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

The 3/23 clone monoclonal antibody specifically binds to CD40, a 40-50 kDa glycoprotein expressed on B lymphocytes and other antigen-presenting cells. CD40 has been reported to be transiently expressed on activated CD4+ and CD8+ T cells and in some mouse strains, the 3/23 mAb has been reported to react with 5-10% of T lymphocytes in adult mouse, but not neonatal, spleen. CD40 plays a key role in B-cell growth and differentiation where interactions of CD40 with its ligand, CD154, are involved in the initiation, effector, and memory stages of cell-mediated immune responses. In addition, CD40 has been reported to be involved with the triggering of NK cells and NK-T cells. Ligation of CD40 with the 3/23 antibody has been reported to induce splenic B cells to express the costimulatory molecule CD86 (B7-2). In addition, although the 3/23 antibody by itself is a weak B-cell mitogen, it has been reported to synergize markedly with mitogenic anti-IgM, anti-IgD mAb or IL-4 to promote B-cell proliferation.

Especificaciones

Especificaciones

CD40
0.5mg/mL
Monoclonal
Rat
Mouse
Mouse CD40 Recombinant Protein
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
3/23
Flow Cytometry
FITC
RUO
Aqueous buffered solution containing ≤0.09% sodium azide.
IgG2a κ
Affinity Purified
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Product Certifications

For Research Use Only.