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CD40 Mouse, anti-Human, FITC, Clone: 5C3, STEMCELL Technologies
Mouse Monoclonal Antibody
135.00€ - 307.80€
Especificaciones
| Antígeno | CD40 |
|---|---|
| Clon | 5C3 |
| Aplicaciones | Immunohistochemistry, Flow Cytometry, Functional Assay |
| Clasificación | Monoclonal |
| Conjugado | FITC |
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|---|---|---|---|---|---|---|---|---|---|
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|
17199121
|
Stemcell Technologies
60113FI.1 |
25 Tests |
135.00€
25 tests |
Fecha estimada de envío: 10-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
|
17189121
|
Stemcell Technologies
60113FI |
100 Tests |
307.80€
100 tests |
Fecha estimada de envío: 10-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
- The 5C3 antibody reacts with CD40, a 45 - 50 kDa type I transmembrane glycoprotein that is a member of the tumor necrosis factor receptor (TNFR) superfamily
- CD40 plays an important role in B cell development and is also involved in the process of B cell selection in germinal centers
- It facilitates T cell-B cell interactions for co-stimulation and immune regulation through engagement with CD154 (gp39), the CD40 ligand expressed on T cells
- In the presence of IL-4, or other stimuli, CD40 promotes B cell proliferation, induces immunoglobulin- (Ig) isotype class switching and rescues B cells from surface Ig-induced apoptosis
- CD40 is expressed on the surface of B cells, follicular dendritic cells, macrophages, fibroblasts, keratinocytes, endothelial cells, basal epithelial cells, CD34+ hematopoietic progenitor cells, and primary carcinomas
- It is expressed at low levels, or not at all, on plasma cells
- The 5C3 antibody has been used for the activation of B cells in in vitro functional assays or for the induction of B cell proliferation
Especificaciones
| CD40 | |
| Immunohistochemistry, Flow Cytometry, Functional Assay | |
| FITC | |
| Baboon, Cynomolgus, Rhesus Monkey, Chimpanzee, Human | |
| Primary |
| 5C3 | |
| Monoclonal | |
| Mouse | |
| IgG1 κ |