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CD4 Rat, anti-Mouse, Alexa Fluor 488, Clone: RM4-5, STEMCELL Technologies

Rat Monoclonal Antibody

Marca:  Stemcell Technologies 60017AD.1

Detalles adicionales : Peso : 0.00110kg

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Código de producto. 17198471

  • 175.56€ / 25 microgramos
Fecha estimada de envío: 22-04-2024
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Descripción

Descripción

  • The RM4-5 antibody reacts with mouse CD4, an ∼55 kDa single-chain type 1 transmembrane glycoprotein and member of the immunoglobulin (Ig) superfamily; CD4 contains four extracellular Ig-like domains
  • CD4 is expressed at relatively high levels by most thymocytes and a subpopulation of T cells (T helper/inducer cells), and at lower levels on dendritic cells
  • CD4 binds to a non-polymorphic region of MHC II and acts as a co-receptor to the T cell receptor (TCR) in MHC II-restricted antigen recognition by enhancing the avidity of the association between the TCR and MHC II-antigen complex
  • Binding of the RM4-5 antibody to CD4 inhibits ligand binding in vitro; binding of the RM4-5 antibody can be blocked by the clone GK1.5 antibody
  • This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse CD4+ T Cell Isolation Kit (Catalog #19852) and EasySep™ Mouse CD25 Regulatory T Cell Positive Selection Kit (Catalog #18782)
Especificaciones

Especificaciones

CD4
Monoclonal
Alexa Fluor 488
25 μg
Mouse
T Cells, T Cells, CD4+, T Cells, Regulatory
Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
RM4-5
Rat
Primary
IgG2a κ
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