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CD31 Rat anti-Mouse, FITC, Clone: MEC 13.3, BD

Rat Monoclonal Antibody

134.00€ - 494.00€

Especificaciones

Antígeno CD31
Clon MEC 13.3
Concentración 0.5mg/mL
Aplicaciones Flow Cytometry
Clasificación Monoclonal
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
15881359
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BD Biosciences
561813
25 μg
134.00€
cada uno
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Fecha estimada de envío: 22-05-2024
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15827188
Ver documentos Detalles de la promoción
BD Biosciences
553372
0.5 mg
494.00€
cada uno
Ver productos alternativos
Ahorre hasta 
»
Fecha estimada de envío: 22-05-2024
para ver el stock
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

The MEC13.3 antibody reacts with CD31, also known as PECAM-1 (Platelet Endothelial Cell Adhesion Molecule-1). CD31 is a 130 kDa integral membrane protein, a member of the immunoglobulin superfamily, that mediates cell-to-cell adhesion. CD31 is expressed constitutively on the surface of adult and embryonic endothelial cells and is also expressed on many peripheral leukocytes and platelets. It has also been detected on bone marrow-derived hematopoietic stem cells and embryonic stem cells. CD31 is involved in the transendothelial emigration of neutrophils, and neutrophil PECAM-1 appears to be down-regulated after extravasation into inflamed tissues. Multiple alternatively spliced isoforms are detected during early post-implantation embryonic development; this alternative splicing is involved in the regulation of ligand specificity. CD38 and vitronectin receptor (αvβ3 integrin, CD51/CD61) are proposed to be ligands for CD31. CD31-mediated endothelial cell-cell interactions are involved in angiogenesis. The MEC13.3 mAb inhibits a variety of in vitro and in vivo functions mediated by CD31.

Especificaciones

Especificaciones

CD31
0.5mg/mL
Monoclonal
Rat
Mouse
129/Sv mouse-derived endothelioma cell line tEnd.1
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
MEC 13.3
Flow Cytometry
FITC
RUO
Aqueous buffered solution containing ≤0.09% sodium azide.
IgG2a κ
Affinity Purified
PECAM-1
Videos
SDS
Documentos

Documentos

Product Certifications

For Research Use Only.