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CD31 (PECAM-1) Rat anti-Mouse, Super Bright 600, Clone: 390, eBioscience™

Rat Monoclonal Antibody

Marca:  Invitrogen 63-0311-82

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15913494

  • 301.00€ / 100 microgramos


Fecha de envío estimada
del proveedor 24-07-2019
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Descripción

Descripción

Please refer to the datasheet for Super Bright Staining Buffer for more information. Light sensitivity: This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (Product No. 00-8222) (100 μL of cell sample + 100 μL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No. 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 405 nm; Emission: 600 nm; Laser: Violet Laser CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.
Especificaciones

Especificaciones

CD31 (PECAM-1)
Monoclonal
0.2 mg/mL
PBS with BSA and 0.09% sodium azide; pH 7.2
Q08481
Pecam1
IgG2b, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
18613
Flow Cytometry
390
Super Bright 600
Pecam1
Liquid
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
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