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CD3 Mouse, anti-Human, APC, Clone: UCHT1, STEMCELL Technologies

Mouse Monoclonal Antibody

Marca:  Stemcell Technologies 100-0448

Detalles adicionales : Peso : 0.00330kg

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Código de producto. 17167611

  • 1111.88€ / 500 tests
Fecha estimada de envío: 22-04-2024
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Descripción

Descripción

  • The UCHT1 antibody reacts with the ∼20 kDa CD3ε subunit of the human T cell receptor (TCR)/CD3 complex, which is expressed on the surface of ∼95% of mature T cells and NKT cells, and variably onthymocytes
  • A majority of T cell neoplasms also express CD3
  • The CD3 complex, which is assembled from combinations of CD3γ, δ, ε, η, and ζ subunits, associates non-covalently with the TCR and is involved in transducing antigen recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR
  • Activation of T cells by the TCR involves the cytoplasmic tails of the CD3 subunits, which are structurally related type 1 transmembrane proteins and members of the immunoglobulin superfamily
  • Mutations in the CD3 subunits have been associated with various immunodeficiency disorders including severe combined immunodeficiency (SCID)
Especificaciones

Especificaciones

CD3
Monoclonal
APC
500 Tests
Chimpanzee, Human
Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
UCHT1
Mouse
Primary
T Cells
Sugerencias de productos

Sugerencias de productos

Videos
SDS
Documentos

Documentos

Certificados
Ofertas especiales

Ofertas especiales