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CD3 Mouse, anti-Human, APC, Clone: UCHT1, STEMCELL Technologies

Mouse Monoclonal Antibody

Marca:  Stemcell Technologies 60011AZ.1

Detalles adicionales : Peso : 0.00110kg

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Código de producto. 17188411

  • 133.00€ / 25 tests
Fecha estimada de envío: 10-11-2022
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Descripción

Descripción

  • The UCHT1 antibody reacts with the ∼20 kDa CD3ε subunit of the human T cell receptor (TCR)/CD3 complex, which is expressed on the surface of ∼95% of mature T cells and NKT cells, and variably onthymocytes
  • A majority of T cell neoplasms also express CD3
  • The CD3 complex, which is assembled from combinations of CD3γ, δ, ε, η, and ζ subunits, associates non-covalently with the TCR and is involved in transducing antigen recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR
  • Activation of T cells by the TCR involves the cytoplasmic tails of the CD3 subunits, which are structurally related type 1 transmembrane proteins and members of the immunoglobulin superfamily
  • Mutations in the CD3 subunits have been associated with various immunodeficiency disorders including severe combined immunodeficiency (SCID)
Especificaciones

Especificaciones

CD3
Monoclonal
APC
25 Tests
Human, Chimpanzee
T Cells
Immunofluorescence, Immunocytochemistry, Flow Cytometry, Western Blot, Immunohistochemistry
UCHT1
Mouse
Primary
IgG1 κ
Videos
SDS
Documentos
Certificados
Ofertas especiales

Ofertas especiales