missing translation for 'onlineSavingsMsg'
Learn More

CD244, Super Bright 645, Clone: eBioC1.7 (C1.7), Monoclonal, eBioscience™

Mouse Monoclonal Antibody

Marca:  Invitrogen 64-5838-41

Detalles adicionales : Peso : 0.01000kg

 Ver más versiones de este producto

Código de producto. 15923664

  • 155.00€ / paquete de 25


Fecha de envío estimada
del proveedor 03-04-2019
Añadir a la cesta

Descripción

Descripción

Super Bright 645 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 645 nm. We recommend using a 660/20 bandpass filter. Please make sure that your instrument is capable of detecting this fluorochrome. When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Staining Buffer (Product No. SB-4400) to minimize any non-specific polymer interactions. Please refer to the datasheet for Super Bright Staining Buffer for more information. Light sensitivity: This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (Product No. 00-8222) (100 μL of cell sample + 100 μL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No. 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 405 nm; Emission: 645 nm; Laser: Violet Laser CD244 (2B4, SLAMF4) is a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via CD244 is thought to modulate NK-cell cytolytic activity. CD244 interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells. Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in the pathology of this autoimmune disease. Diseases associated with CD244 dysfunction include rheumatoid arthritis and lymphoproliferative syndrome. Alternatively spliced transcript variants encoding different isoforms of CD244 have been found for this gene.
Especificación

Especificación

CD244
Monoclonal
5 μL/Test
PBS with BSA and 0.09% sodium azide; pH 7.2
Q9BZW8
2B4; CD244; CD244 molecule, natural killer cell receptor 2B4; h2B4; NAIL; Natural killer cell receptor 2B4; NK cell activation inducing ligand NAIL; NK cell activation-inducing ligand; NK cell type I receptor protein 2B4; NKR2B4; Nmrk; Signaling lymphocytic activation molecule 4; SLAM family member 4; SLAMF4
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
eBioC1.7 (C1.7)
Super Bright 645
CD244
Liquid
CD244
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
51744
Videos