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CD244 Mouse anti-Human, Super Bright 436, Clone: eBioC1.7 (C1.7), eBioscience™

Mouse Monoclonal Antibody

Marca:  Invitrogen 62-5838-41

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15933434

  • 146.00€ / paquete de 25


Fecha de envío estimada
del proveedor 27-11-2019
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Descripción

Descripción

Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm. We recommend using a 450/50 bandpass filter, or equivalent. Please make sure that your instrument is capable of detecting this fluorochrome. When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Complete Staining Buffer (Product No. SB-4401) to minimize any non-specific polymer interactions. Please refer to the datasheet for Super Bright Staining Buffer for more information. Excitation: 405 nm; Emission: 436 nm; Laser: Violet Laser Super Bright Polymer Dyes are sold under license from Becton, Dickinson and Company. CD244 (2B4, SLAMF4) is a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via CD244 is thought to modulate NK-cell cytolytic activity. CD244 interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells. Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in the pathology of this autoimmune disease. Diseases associated with CD244 dysfunction include rheumatoid arthritis and lymphoproliferative syndrome. Alternatively spliced transcript variants encoding different isoforms of CD244 have been found for this gene.
Especificaciones

Especificaciones

CD244
Monoclonal
5 μL/Test
PBS with BSA and 0.09% sodium azide; pH 7.2
Q9BZW8
2B4, NAIL, NKR2B4, Nmrk, SLAMF4, NK cell activation inducing ligand NAIL, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, h2B4, natural killer cell receptor 2B4
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
eBioC1.7 (C1.7)
Super Bright 436
CD244
Liquid
CD244
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
51744
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