Learn More
CD226 (DNAM-1) Monoclonal Antibody (11A8.7.4), PE-Cyanine7, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
en la oferta
Especificaciones
Antígeno | CD226 (DNAM-1) |
---|---|
Clon | 11A8.7.4 |
Concentración | 5 μL/Test |
Aplicaciones | Flow Cytometry |
Clasificación | Monoclonal |
Descripción
The monoclonal antibody 11A8.7.4 reacts to DNAM-1 also known as CD226. DNAM 1 is a 65 kD receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. The ligands for CD226 are the poliovirus receptor (PVR, CD155) and Poliovirus Related Receptor (PPR2, Nectin-2, CD112). CD226 is involved in cytolytic activity by interacting with integrins and activating protein tyrosine kinase Fyn. The 11A8.7.4 antibody has been shown to increase T and NK cell-mediated cytotoxicity. Applications Reported: This 11A8.7.4 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 11A8.7.4 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (Product No.
CD226 (DNAM-1) Monoclonal antibody specifically detects CD226 (DNAM-1) in Human samples. It is validated for Flow Cytometry.Especificaciones
CD226 (DNAM-1) | |
5 μL/Test | |
Monoclonal | |
Liquid | |
RUO | |
Q15762 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |
11A8.7.4 | |
Flow Cytometry | |
PE-Cyanine7 | |
Mouse | |
Human | |
10666 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! |