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CD223 (LAG-3) Mouse anti-Human, Super Bright 645, Clone: 3DS223H, eBioscience™

Mouse Monoclonal Antibody

Marca:  Invitrogen 64-2239-42

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15933644

  • 330.00€ / paquete de 100


Fecha de envío estimada
del proveedor 28-11-2019
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Descripción

Descripción

When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Complete Staining Buffer (Product No. SB-4401) to minimize any non-specific polymer interactions. Please refer to the datasheet for Super Bright Staining Buffer for more information. Light sensitivity: This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (Product No. 00-8222) (100 μL of cell sample + 100 μL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No. 00-5333) for up to 3 days in the dark at 4 degrees C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 405 nm; Emission: 645 nm; Laser: Violet Laser Super Bright Polymer Dyes are sold under license from Becton, Dickinson and Company. LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).
Especificaciones

Especificaciones

CD223 (LAG-3)
Monoclonal
5 μL/Test
PBS with BSA and 0.09% sodium azide; pH 7.2
P18627
CD223; LAG-3; Ly66; Lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Protein FDC
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
3DS223H
Super Bright 645
LAG3
Liquid
LAG3
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3902
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