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CD161 Mouse anti-Human, FITC, Clone: DX12, BD
Mouse Monoclonal Antibody
453.00€ - 670.00€
Especificaciones
| Antígeno | CD161 |
|---|---|
| Clon | DX12 |
| Aplicaciones | Flow Cytometry |
| Clasificación | Monoclonal |
| Conjugado | FITC |
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|---|---|---|---|---|---|---|---|---|---|
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|
15825918
|
BD Biosciences
340536 |
50 Tests |
670.00€
cada uno |
Fecha estimada de envío: 21-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
|
15808638
|
BD Biosciences
556080 |
100 Tests |
453.00€
cada uno |
Fecha estimada de envío: 21-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
The DX12 monoclonal antibody specifically binds to human CD161 which is also known as Natural killer cell surface protein P1A (NKR-P1A). CD161 is encoded by the KLRB1 (Killer cell lectin-like receptor subfamily B member 1) gene. CD161 is a member of the C-type lectin superfamily and is also referred to as C-type lectin domain family 5 member B (CLEC5B). CD161 is a 80 kDa disulfide-linked homodimer, type II membrane glycoprotein. CD161 is expressed mostly on NK cell populations and on subsets of CD4+ and CD8+ αβ T cells, NKT cells and γδ T cells. Reports indicate that CD161 is expressed preferentially on CD45RO+ T cells, however, it can be found on a subset of thymocytes and fetal liver T cells. Its function has not been fully elucidated, but reports indicate that NKR-P1A may serve as a specific receptor for some NK cell targets. The DX12 antibody can reportedly inhibit spontaneous cytotoxicity mediated by certain NK cell clones.
Especificaciones
| CD161 | |
| Flow Cytometry | |
| FITC | |
| RUO | |
| Human | |
| IgG1 κ |
| DX12 | |
| Monoclonal | |
| Mouse | |
| Immunology | |
| Human NKR-P1A Transfected Mouse Fibroblasts | |
| Primary |
For Research Use Only.