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CD16 Mouse anti-Baboon, Chimpanzee, Cynomolgus Monkey, Human, Non-human primate, Rhesus Monkey, Super Bright 436, Clone: 3G8, eBioscience™

Mouse Monoclonal Antibody

Marca:  Invitrogen 62-0166-42

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15923354

  • 278.00€ / paquete de 100


Fecha estimada de envío
25-08-2020
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Descripción

Descripción

Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm. We recommend using a 450/50 bandpass filter, or equivalent. Please make sure that your instrument is capable of detecting this fluorochrome. When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Complete Staining Buffer (Product No. SB-4401) to minimize any non-specific polymer interactions. Please refer to the datasheet for Super Bright Staining Buffer for more information. Excitation: 405 nm; Emission: 436 nm; Laser: Violet Laser Super Bright Polymer Dyes are sold under license from Becton, Dickinson and Company. CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FCGR3A is associated, with FcepsilonRI-beta subunit. Besides IgG, FCGR3A can be triggered also by oligomeric IgE. FCGR3B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a pro-adhesive phenotype. Diseases associated with CD16 dysfunction include immunodeficiency 20 and systemic lupus erythematosus.
Especificaciones

Especificaciones

CD16
Monoclonal
5 μL/Test
PBS with BSA and 0.09% sodium azide; pH 7.2
O75015, P08637
FCGR3A, FCGR3B
IgG1
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
2214, 2215
Flow Cytometry
3G8
Super Bright 436
FCGR3B
Liquid
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Baboon, Chimpanzee, Cynomolgus Monkey, Human, Non-human primate, Rhesus Monkey
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