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CD16/CD32 Rat anti-Mouse, Super Bright 600, Clone: 93, eBioscience™

Rat Monoclonal Antibody

Marca:  Invitrogen 63-0161-82

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15923474

  • 302.00€ / 100 microgramos


Fecha estimada de envío
20-08-2020
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Descripción

Descripción

Please protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (Product No. 00-8222) (100 μL of cell sample + 100 μL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No. 00-5333) for up to 3 days in the dark at 4 degrees C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 405 nm; Emission: 600 nm; Laser: Violet Laser Super Bright Polymer Dyes are sold under license from Becton, Dickinson and Company. CD16 is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by natural killer (NK) cells, and some T cells and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC (antibody dependent cell mediated cytotoxicity) by NK cells. IN comparison, CD32 is a 40 kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII), and mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. Further, CD32 is involved in the phagocytosis of immune complexes, the regulation of antibody production by B-cells, and variations of the CD32 gene may increase vulnerability to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms of CD32 have been found.
Especificaciones

Especificaciones

CD16/CD32
Monoclonal
0.2 mg/mL
PBS with BSA and 0.09% sodium azide; pH 7.2
P08101
Fcgr2b
IgG2a, lambda
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
14130
Flow Cytometry
93
Super Bright 600
Fcgr2b
Liquid
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
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