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C19orf62 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 27926-1-AP-150UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16815905

  • 319.00€ / 150 microlitros

Envío estimado: 21-10-2021

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Descripción

Descripción

HSPC142 is a component of the BRCA1-A complex, a complex that specifically recognizes ′Lys-63′-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes ′Lys-63′-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. HSPC142 probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves ′Lys-63′-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the ′Lys-63′-linked deubiquitinase activity mediated by BRCC3/BRCC36.
Especificaciones

Especificaciones

C19orf62
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9NWV8
BABAM1, C19orf62, HSPC142, MERIT40, NBA1
Rabbit
IgG
150 μL
-20°C
Primary
29086
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
BABAM1
Liquid
BABAM1
C19orf62 Fusion Protein Ag27459
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Videos
SDS
Documentos
Certificados