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ACROBiosystems Biotinylated Human OX40 Ligand / TNFSF4 Protein, His, Avitag™

Biotinylated Protein

Marca:  ACROBiosystems OXL-H82Q6-25ug

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16477939

  • 391.16€ / 25 microgramos
Fecha estimada de envío: 02-08-2022
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Descripción

Descripción

Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membrane-bound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46% amino acid sequence identity with its mouse counterpart.

This protein carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 19.1 kDa. The protein migrates as 25-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

NP_003317.1
19.1 kDa
25 µg
Gln 51 - Leu 183
OX40L,TNFSF4,CD252,Glycoprotein Gp34,TXGP1,CD134 ligand,CD134L
Precision Avi
PBS, pH7.4
HEK293
Human
Powder
>90% as determined by SDS-PAGE
Biotinylated Human O x 40 Ligand, His,Avitag (OXL-H82Q6) is expressed from human 293 cells (HEK293). It contains AA Gln 51 - Leu 183 (Accession # P23510-1).
-20°C
OX40 Ligand
His Tag and Avi Tag
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
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