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ATPIF1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 12067-1-AP-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16819563

  • 109.00€ / 20 microlitros

Envío estimado: 21-10-2021

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Descripción

Descripción

Complex V, also called F1F0 ATPase or ATP synthase is extremely conserved through evolution and can be found in plants, fungi, bacteria, and animals. The ATP synthase enzyme is a transmembrane protein responsible for driving the reversible reaction from ADP + phosphate to ATP, in oxidative phosphorylation, and as a proton pumping ATPase. This reaction is accomplished by a flux of protons across the membrane as a result of electron transfer. The enzyme was thought to be localized exclusively to mitochondria; however, it has recently been identified on the plasma membrane of several cell types including hepatocytes where it functions as the HDL receptor, on endothelial cells where it may act as the angiostatin receptor, and on the surface of cancer cells. The ATP synthase protein has two main sections; the F1 ATP-ase (soluble) and the F0 ATP-ase (membrane embedded). The F1 section consists of the alpha, beta, gamma, delta, and epsilon subunits; while the F0 consists of a, b, and c subunits. The enzyme in mammals is composed of 17 subunits, five of which make up the easily detached F1. The remainder subunits are components of two stalk domains and the proton pumping F0 part of the machinery. Two of the subunits of the F0 part are encoded on mitochondrial DNA while the other subunits are nuclearly encoded. Mutations in the mitochondrial-encoded subunits of ATP synthase (Complex V) cause OXPHOS disease.
Especificaciones

Especificaciones

ATPIF1
0.41 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9UII2
ATPase inhibitory factor 1, ATPI, ATPIF1, ATPIP, IF(1), IF1, Inhibitor of F(1)F(o) ATPase, IP
Rabbit
IgG
20 μL
-20°C
Primary
93974
Western Blot, Immunoprecipitation, Immunofluorescence, Immunocytochemistry
Unconjugated
ATPIF1
Liquid
ATPIF1
ATPIF1 Fusion Protein Ag2704
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Videos
SDS
Documentos
Certificados