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ASH2L Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 12331-1-AP-20UL

Detalles adicionales : Peso : 0.00010kg

 Ver más versiones de este producto

Código de producto. 16819993

  • 109.00€ / 20 microlitros

Envío estimado: 02-11-2021

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Descripción

Descripción

The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1, or isoform 1, which contains a nuclear localization signal and PHD finger motif, suggesting that the gene product functions as a transcription regulator. Alternative splicing results in a shorter isoform 2, designated ASH2L2, which is missing the first 94 amino acid residues found in ASH2L1. Human ASH2L proteins are 60% homologous to Drosophila ash2, which positively regulates expression of certain genes in early development, and contain similar, but not identical, domains, including a zinc finger motif. ASH2L is highly expressed in fetal liver, testis and leukemia cell lines with erythroid and megakaryocytic potential, such as K562, Hel and Dami. Differentiation inducers (e.g. phorbol ester and hemin) cause different expression patterns in these cells lines, suggesting that ASH2L plays a role in hematopoiesis and is associated with particular types of leukemia.
Especificaciones

Especificaciones

ASH2L
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q91X20, Q9UBL3
ASH2, ASH2 like protein, ASH2L, ASH2L1, ASH2L2, Bre2
Rabbit
IgG
20 μL
-20°C
Primary
23808, 290829, 9070
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Unconjugated
ASH2L
Liquid
Ash2l
ASH2L Fusion Protein Ag3008
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Non-human Primate, Rat, Mouse
Videos
SDS
Documentos
Certificados