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APBA2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 19781-1-AP-20UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16819264

  • 140.00€ / 20 microlitros
Fecha estimada de envío: 17-04-2024
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Descripción

Descripción

APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer′s disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer′s disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.
Especificaciones

Especificaciones

APBA2
Polyclonal
Unconjugated
APBA2
Adapter protein X11beta, APBA2, D15S1518E, HsT16821, LIN 10, Mint 2, MINT2, Neuron specific X11L protein, X11L
Rabbit
Antigen Affinity Chromatography
RUO
11784, 321
-20°C
Liquid
Western Blot
0.14 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P98084, Q99767
Apba2
Peptide
20 μL
Primary
Human, Mouse
Antibody
IgG
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Ofertas especiales