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VASP Mouse, Unlabeled, Clone: 43, BD

Mouse Monoclonal Antibody

Marca:  BD Biosciences 610447

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15825469

  • 343.00€ / 1 set
Fecha estimada de envío: 22-04-2024
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Descripción

Descripción

Vasodilator-stimulated phosphoprotein (VASP), a substrate for cAMP- and cGMP-dependent kinases, is associated with actin filaments, focal adhesions, and dynamic membrane regions. VASP is composed of several distinct domains: a central L-proline-rich domain contains a GPPPPP motif as a single copy and as a three-fold tandem repeat, as well as three conserved phosphorylation sites for cyclic nucleotide-dependent protein kinases (Ser157, Ser239, and Thr278). A C-terminal domain contains a repetitive mixed-charge cluster which is predicted to form an α-helix. The C-terminal domain appears to be responsible for anchoring at focal adhesion sites. VASP has been shown to be a ligand for profilins. Profilins bind to the poly-L-proline motifs of VASP and it is postulated that these two molecules act in concert to convey signal transduction to actin filament formation.

Immunofluorescence, Immunoprecipitation, Western Blotting

Especificaciones

Especificaciones

VASP
Monoclonal
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
50 μg
Cell Biology
Canine, Human
IgG1
Western Blot
43
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Sugerencias de productos

Sugerencias de productos

Videos
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Documentos

Documentos

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Ofertas especiales

Ofertas especiales

For Research Use Only.