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Phospho-PKC delta (Tyr52) Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Marca:  Invitrogen PA538417

Detalles adicionales : Peso : 0.00900kg

Código de producto. 15545341

  • 339.00€ / 100 microgramos


Fecha de envío estimada
del proveedor 28-11-2019
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Descripción

Descripción

Protein Kinase C delta (PKC delta) is a 78 kDa member of the novel group (nPKCs: sensitive to diacylglycerol, phosphatidylserine, and phorbol esters) of the PKC family of serine/threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC delta is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of multiple cellular processes including cell cycle progression and apoptosis. Autophosphorylation of serine 664 (serine 662 in mouse and rat) contributes to PKC delta activity. Serum dependent phosphorylation of serine 664 is mediated by mTOR pathway, is protected from dephosphorylation by phosphorylated threonine 505 in the activation loop, and is implicated in prolactin signaling.
Especificaciones

Especificaciones

Phospho-PKC delta (Tyr52)
Polyclonal
Unconjugated
PRKCD
Liquid
PRKCD
A synthetic phosphopeptide derived from human PKC sigma around the phosphorylation site of Tyr52 (T-M-YP-P-E)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Q05655, P28867, P09215
Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta, Sphingosine-dependent protein kinase-1, SDK1, PRKCD, PKC delta
Rabbit
IgG
100 μg
-20°C
Primary
170538, 18753, 5580
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