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MEF2D Mouse, Unlabeled, Clone: 9, BD

Mouse Monoclonal Antibody

343.00€ - 675.00€

Especificaciones

Antígeno MEF2D
Clon 9
Concentración 250μg/mL
Aplicaciones Western Blot
Clasificación Monoclonal
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
15815639
Ver documentos Detalles de la promoción
BD Biosciences
610774
50 μg
343.00€
1 set
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Fecha estimada de envío: 23-04-2024
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15825639
Ver documentos Detalles de la promoción
BD Biosciences
610775
150 μg
675.00€
1 set
Ver productos alternativos
Ahorre hasta 
»
Fecha estimada de envío: 23-04-2024
para ver el stock
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

MEF2D is a member of the MEF2 (Myocyte-specific Enhancer-binding Factor 2) transcription factor family. Members of this family (MEF2A, B, C, & D) contain several characteristic motifs that include a MEF2 domain and a MADS box. MEF2 proteins bind the DNA sequence, 5′- (C/T)T(A/T)(A/T)AAATA(A/G)-3′, and binding occurs primarily, although not exclusively, in muscle cells. MEF2D gene expression is ubiquitous and the mRNA is alternatively spliced. This results in multiple protein isoforms that heterodimerize with other family members. In addition to the MEF2 and MADS domains, MEF2D has a glutamine-/proline-rich region, amino acids 365-404, and a basic region, in the MADS domain near the N-terminus. The glutamine-/proline-rich region is involved in transactivation, while the basic region mediates sequence-specific DNA binding. MEF2D displays 75% similarity to hMEF2A and hMEF2C. Myogenin gene transcription requires MEF2D, indicating that MEF2D is involved in myogenesis and muscle cell differentiation. MEF2D has been reported to have a calculated molecular weight of 56kDa, but can be observed migrating in a range of 56-70kDa.

Immunofluorescence, Immunoprecipitation, Western Blotting

Especificaciones

Especificaciones

MEF2D
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG1
Affinity Purified
Myocyte-specific Enhancer-binding Factor 2
9
Western Blot
Unconjugated
RUO
Canine, Human, Mouse, Rat
Mouse MEF2D aa. 346-511
Primary
Store undiluted at -20°C.
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For Research Use Only.