missing translation for 'onlineSavingsMsg'
Learn More

Ki-67 Mouse anti-Human, Unlabeled, Clone: 35, BD

Mouse Monoclonal Antibody

241.00€ - 416.80€

Especificaciones

Antígeno Ki-67
Isotipo IgG1
Inmunógeno Human Ki-67 aa. 1547-1742
Formulación Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugado Unconjugated
Ver más especificaciones

Productos 2
Código de producto Marca Cantidad. Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad. Precio Cantidad y disponibilidad  
15815739 Ver documentos BD Biosciences
610968
50μg 241.00€
1 set Ver productos alternativos
Ahorre hasta 
»
Fecha estimada de envío
07-10-2019
Añadir a la cesta
 
15825739 Ver documentos BD Biosciences
610969
150μg 416.80€
1 set Ver productos alternativos
Ahorre hasta 
»
Fecha estimada de envío
07-10-2019
Añadir a la cesta
 
Descripción

Descripción

Cellular proliferation is a complex multi-faceted process, central to biological events ranging from embryonic development to wound healing. Although proliferation is tightly controlled, dysregulation often results in tumorigenesis. The regulatory process involves the expression of many cell-cycle-associated proteins that are subject to cycle-dependent modification. Such protein expression may be monitored to assess the proliferative capacity of cells, especially tumorigenic cells.The Ki-67 antigen is a nuclear protein expressed exclusively in proliferating cells during all active parts of the cell cycle. However, it is absent in quiescent cells and during DNA repair. The distribution of Ki-67 changes during different stages of the cell cycle. During G1, it is localized to the perinuclear region, but is primarily found in the nuclear matrix in later phases. During mitosis, it associates with the condensed chromosomes. The nuclear localization of Ki-67 and strict association with the cell cycle indicate its importance in the regulation of cell division. Therefore, Ki-67 has become an important marker of proliferating cells, and may also be a marker for disitinct nuclear matrix compartments.

Immunofluorescence, Western Blotting

Especificaciones

Especificaciones

Ki-67
Human Ki-67 aa. 1547-1742
Unconjugated
Cell Biology
Murine
Affinity Purified
Monoclonal
Store undiluted at -20°C.
IgG1
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
35
250μg/mL

For Research Use Only.