missing translation for 'onlineSavingsMsg'
Learn More

Gαq Mouse, Unlabeled, Clone: 10, BD

Mouse Monoclonal Antibody

259.00€ - 416.80€

Especificaciones

Antígeno Gαq
Isotipo IgG1
Inmunógeno Human Gαq aa. 22-31
Formulación Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugado Unconjugated
Ver más especificaciones

Productos 2
Código de producto Marca Cantidad. Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad. Precio Cantidad y disponibilidad  
15816269 Ver documentos BD Biosciences
612704
50μg 259.00€
cada uno Ver productos alternativos
Ahorre hasta 
»
Fecha estimada de envío
04-10-2019
Añadir a la cesta
 
15826269 Ver documentos BD Biosciences
612705
150μg 416.80€
cada uno Ver productos alternativos
Ahorre hasta 
»
Fecha estimada de envío
04-10-2019
Añadir a la cesta
 
Descripción

Descripción

The GTP binding regulatory proteins (G proteins) consist of three subunits: α, β, and γ. These heterotrimeric proteins function at membranes to relay signals from cell surface receptors to intracellular effectors. The α subunit is unique for each G protein and contains the site of GTP binding and hydrolysis, as well sites for receptor and effector interactions. The βγ subunit complex interacts directly with receptors and the α subunit. The Gα family includes four families: the Gαs family including Gαs , Gαo1f, and Gαt, the Gαi family including Gαi, Gαo, and Gαz, the Gαq/Gα11 family and the Gα12/13 family. The Gαq protein is 88% homologus with Gα11 and both are widely expressed. These G proteins activate phospholipase C proteins, which induce calcium signaling events. G protein coupled receptors (GPCRs) involved in regulating Wnt signaling activate Gαq, phospholipase Cβ, and induce calcium-dependent activation of calpain. These events promote β-catenin nuclear export and proteolysis. Gαq has also been implicated in metabotropic glutamate receptor signaling. Thus, Gαq isoforms activate phospholipase C proteins in various G-protein coupled receptor pathways.

Immunofluorescence, Western Blotting

Especificaciones

Especificaciones

Gαq
Human Gαq aa. 22-31
Unconjugated
Cell Biology
Murine
Affinity Purified
Monoclonal
Store undiluted at -20°C.
IgG1
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
10
250μg/mL

For Research Use Only.