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EB1 Mouse, Unlabeled, Clone: 5, BD

Mouse Monoclonal Antibody

Marca:  BD Biosciences 610535

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15825509

  • 565.00€ / 1 set
Fecha estimada de envío: 23-04-2024
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Descripción

Descripción

Familial adenomatous polyposis is an autosomal inherited disease characterized by mutations in the APC (adenomatous polyposis coli) gene. Individuals with this disease are predisposed to colorectal polyps and cancer. It has been proposed that disruption of the APC gene plays a role in the disease. APC is a large coiled-coil protein that interacts, via its carboxy terminus, with catenins and with the protein, EB1. This 30kDa protein was discovered as a result of its strong binding to the C-terminal domain of APC. Like the APC-binding proteins β-Catenin and pp120Cas, EB1 may play an essential role in modulating APC activity and tumorigenesis.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Especificaciones

Especificaciones

EB1
Monoclonal
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
150 μg
Cell Biology
Chicken, Human, Mouse, Rat
IgG1
Western Blot
5
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Sugerencias de productos

Sugerencias de productos

Videos
SDS
Documentos

Documentos

Certificados
Ofertas especiales

Ofertas especiales

For Research Use Only.