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Desmoglein Mouse, Unlabeled, Clone: 62, BD

Mouse Monoclonal Antibody

Marca:  BD Biosciences 610273

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15825379

  • 343.00€ / 1 set
Fecha estimada de envío: 22-04-2024
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Descripción

Descripción

Desmoglein (Dsg1) is a transmembrane glycoprotein found in desmosome junctions. Desmosomes and adherens junctions are plasma membrane specializations involved in cell-cell adhesion. They serve as membrane anchorage domains for intermediate filaments and microfilaments, respectively. Actin microfilaments anchor at adherens junctions, which occur in many sizes, shapes, and positions. These junctions generally contain E- or N-Cadherin whose cytoplasmic region is associated with cytoplasmic proteins such as α- and β- catenin, vinculin, α-actinin, and radixin. Intermediate filaments (IFs) are anchored at desmosomes which contain desmosome-specific cadherin family members, known as desmocollin (Dsc) and desmoglein. These proteins associate with cytoplasmic proteins such as desmoplakin and plakoglobin (γ-Catenin). Plakoglobin is the only junctional protein found at both desmosomes and adherens junctions and, therefore, plays a crucial role in cell adhesion.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Especificaciones

Especificaciones

Desmoglein
Monoclonal
250μg/mL
Dsg1
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Western Blot
62
Unconjugated
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
50 μg
Cell Biology
Canine, Chicken, Drosophila, Human, Mouse, Rat
IgG2b
Sugerencias de productos

Sugerencias de productos

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Documentos

Documentos

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Ofertas especiales

Ofertas especiales

For Research Use Only.