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Cyclin B1 Mouse, Unlabeled, Clone: GNS-1, BD

Mouse Monoclonal Antibody

Marca:  BD Biosciences 554176

Detalles adicionales : Peso : 0.01000kg

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Código de producto. 15887598

  • 337.44€ / cada uno
Fecha estimada de envío: 17-02-2023
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Descripción

Descripción

Cyclins and cyclin-dependent kinases (cdks) are evolutionarily conserved proteins that are essential for cell-cycle control in eukaryotes. Cyclins (regulatory subunits) bind to cdks (catlytic subunits) to form complexes that regulate the progression of the cell cycle. The main cyclin-cdks complexes formed in vertebrate cells are cyclin D-cdk4 (G0/G1), cyclin E-cdk2 (G1/S), cyclin A-cdk2 (S) and cyclin B1-cdk1 (G2/M). These complexes are regulated by activating and inhibitory phosphorylation events, as well as by interactions with small regulatory proteins, such as p21 and p27 [Kip1]. Cyclin B1 is a mitotic cyclin, where expression is normally low in G0/G1, increases in S and is maximal during the G2/M phase. Cyclin B1 is rapidly degraded at the end of mitosis, and is required for cells to exit from mitosis. This antibody has been reported to react to hamster and mouse cyclin B1. In addition, the GNS-1 antibody has been reported to recognize an epitope between amino acids 1-21 of human cyclin B1.

Host Species: Mouse
Clone: GNS-1
Isotype: IgG1
Species Reactivity: Human
Immunogen: Human Cyclin B1 Recombinant Protein
Formula Weight [Chemical]: 62kDa

Bioimaging, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blotting

Especificaciones

Especificaciones

Cyclin B1
Monoclonal
0.5mg/mL
Aqueous buffered solution containing ≤0.09% sodium azide.
Human Cyclin B1 Recombinant Protein
0.1 mg
Cell Biology
Mouse, Human, Hamster
IgG1
Western Blot
GNS-1
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at 4°C
Videos
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Documentos

Documentos

Certificados
Ofertas especiales

Ofertas especiales

For Research Use Only.