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CD9 Rat anti-Mouse, NA/LE, Unlabeled, Clone: KMC8, BD
Rat Monoclonal Antibody
Marca: BD Biosciences 553758
Detalles adicionales : Peso : 0.01000kg
Descripción
The KMC8 antibody reacts with CD9, a 24kDa member of the transmembrane 4 superfamily. In the mouse, CD9 is present on bone marrow myeloid cells, stromal cells, and megakaryocyte-committed progenitors; subsets of peripheral T and B lymphocytes; and neutrophils, platelets, dendritic cells, and bone marrow-derived macrophages. CD9 has been found to be associated with integrins and other cell-surface receptors, and it is suggested to play a role in signal transduction and possibly in regulating cellular adhesive properties. It has also been demonstrated to participate in T-cell costimulation and induction of apoptosis. The KMC8 antibody has been reported to block certain CD9 functions and activate macrophages.
Host Species: Rat
Clone: KMC8
Isotype: IgG2a κ
Species Reactivity: Mouse
Immunogen: (C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal cell line BMS2
Blocking Assay, Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blotting
Especificaciones
| CD9 | |
| Monoclonal | |
| 1.0mg/mL | |
| No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay. | |
| (C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal cell line BMS2 | |
| 0.5 mg | |
| Immunology | |
| Mouse | |
| IgG2a κ |
| Flow Cytometry | |
| KMC8 | |
| Unconjugated | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
For Research Use Only.