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CD40 Mouse anti-Human, NA/LE, Unlabeled, Clone: 5C3, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 555586
Detalles adicionales : Peso : 0.01000kg
Descripción
This antibody reacts with a 45-48kDa type I integral membrane glycoprotein present on peripheral blood and tonsillar B cells, but not expressed on terminally differentiated B cells. CD40 is also present on some epithelial cells, carcinomas and lymphoid dendritic cells. This antibody is useful for studies of B-cell growth and function. Anti-CD40 antibodies have been reported to stimulated B-cell proliferation when costimulated with anti-?, anti-CD20 antibodies or with phorbol esters. 5C3 is capable of inducing B-cell proliferation when presented with IL-4. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only.
Especificaciones
| CD40 | |
| Monoclonal | |
| 1.0mg/mL | |
| TNFRSF5; TNF receptor superfamily member 5; CD40L receptor; Bp50; p50 | |
| Mouse | |
| 0.5 mg | |
| Immunology | |
| Human | |
| IgG1 κ |
| Flow Cytometry | |
| 5C3 | |
| Unconjugated | |
| No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay. | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
For Research Use Only.