missing translation for 'onlineSavingsMsg'
Learn More

E-cadherin Monoclonal Antibody (67A4), FITC, Invitrogen™

Mouse Monoclonal Antibody

Marca:  Invitrogen MA110194

255.34 EUR hasta el 2024-03-29
Use el código promocional "21615" para aplicar la oferta.



Detalles adicionales : Peso : 0.01000kg

Código de producto. 12372213

  • 383.00€ / paquete de 100
Fecha estimada de envío: 23-04-2024
para ver el stock

Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.


Descripción

Descripción

E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintece of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.
Especificaciones

Especificaciones

E-cadherin
Monoclonal
FITC
P12830
CDH1
T-47D cells
100 Tests
Primary
Human
Antibody
IgG1
Flow Cytometry, Immunocytochemistry, Immunofluorescence
67A4
CDH1
Arc-1, CD324, CDHE, ECAD, LCAM, UVO, CAM 120/80, E-Cadherin, cadherin 1, E-cadherin epithelial, cadherin-1, calcium-dependent adhesion protein, epithelial, cell-CAM 120/80, epithelial cadherin, uvomorulin, cadherin-E
Mouse
Purified
RUO
999
4° C, store in dark, DO NOT FREEZE!
Liquid
Sugerencias de productos

Sugerencias de productos

Videos
SDS
Documentos

Documentos

Certificados
Ofertas especiales

Ofertas especiales