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ACTN4 Mouse anti-Human, Mouse, Rat, Clone: 1E12B8, Proteintech

Mouse Monoclonal Antibody

Marca:  Proteintech 66628-1-IG-150UL

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16818685

  • 319.00€ / 150 microlitros

Envío estimado: 21-10-2021

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Descripción

Descripción

This antibody recognizes 105 kDa of endogenous ACTN4 protein in various lysates.

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
Especificaciones

Especificaciones

ACTN4
1E12B8
Unconjugated
ACTN4
Liquid
Actn4
ACTN4 Fusion Protein Ag13549
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O43707, P57780, Q9QXQ0
ACTININ 4, actinin, alpha 4, ACTN4, Alpha actinin 4, F actin cross linking protein, FSGS, FSGS1, Non muscle alpha actinin 4
Mouse
IgG1
150 μL
-20°C
Primary
60595, 63836, 81
Videos
SDS
Documentos
Certificados