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OLFM4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Thermo Scientific PA5115687
Detalles adicionales : Peso : 0.01000kg
Descripción
Antibody detects endogenous levels of total OLFM4.
OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflammed colonic epithelium. It has one signal peptide, six N-linked glycosylation motif and forms disulfide-bonded multimers. OLFM4 a transcription factor may have a matrix-related function in differentiation. Constitutively expressed OLFM4 in cancer cells binds to the potent apoptosis inducer GRIM-19 and has a novel antiapoptotic action and hence might serve as a diagnostic marker for human cancers. Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2/M phase. Potential interaction of OLFM4 with endogenous cell surface lectins and cadherins may mediate cell adhesion.Especificaciones
| OLFM4 | |
| Polyclonal | |
| Unconjugated | |
| OLFM4 | |
| Antiapoptotic protein GW112; bA209J19.1; GC1; G-CSF-stimulated clone 1 protein; Gm296; Gm913; GW112; hGC-1; hOLfD; olfactomedin 4; olfactomedin-4; OlfD; OLFM4; OLM4; pPD4; PU.1 difference product 4; UNQ362; UNQ362/PRO698 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 10562, 290409, 380924 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q3UZZ4, Q6UX06 | |
| OLFM4 | |
| A synthesized peptide derived from human OLFM4(Accession Q6UX06), corresponding to amino acid residues N253-Y303. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |