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Iduronate 2 Sulfatase Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA595962
Detalles adicionales : Peso : 0.01000kg
Descripción
Immunogen sequence: TDALNVLLII VDDLRPSLGC YGDKLVRSPN IDQLASHSLL FQNAFAQQAV CAPSRVSFLT GRRPDTTRLY DFNSYWRVHA GNFSTIPQYF KENGYVTMSV GKVFHPGISS NHTDDSPYSW SFPPYHPSSE KYENTKTCRG PDGELHANLL CPVDVLDVPE GTLPDKQSTE QAIQLLEKMK TSASPFFLAV GYHKPHIPFR YPKEFQKLYP LENITLAPDP EVPDGLPPVA YNPWMDIRQR EDVQALNISV PYGPIPV; Positive Samples: HepG2, A-549, HT-1080, Mouse kidney, Rat kidney; Cellular Location: Lysosome
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.Especificaciones
| Iduronate 2 Sulfatase | |
| Polyclonal | |
| Unconjugated | |
| Ids | |
| alpha-L-iduronate sulfate sulfatase, AW214631, Ids, Iduronate 2-sulfatase, iduronate 2-sulfatase (Hunter syndrome), iduronate 2-sulfatase 14 kDa chain, Iduronate 2-sulfatase 42 kDa chain, iduronate sulfatase, iduronate-2-sulfatase, idursulfase, MPS2, SIDS | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 15931, 3423, 363513 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| 0.2 mg/mL | |
| PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3 | |
| P22304, Q08890 | |
| Ids | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 34-290 of human IDS (NP_0001931) | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |