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Cytiva HiTrap™ MabSelect™ Prepacked Columns
Use these columns in small-scale MAb purification in a continuous bioprocess. Cytiva Life Sciences™ HiTrap™ MabSelect™ Prepacked Columns for fast purification of monoclonal antibodies (Mabs) from large sample volumes
Marca: Cytiva 28-4082-56
Detalles adicionales : Peso : 0.02500kg
Descripción
Prepacked HiTrap columns for process development, screening of purification conditions, and small-scale purification of Mabs. MabSelect media are suited for the high flowrates and pressures required when scaling up.
- Oriented coupling of recombinant Protein A ligand to the agarose matrix via an engineered C-terminal cysteine increases IgG binding capacity over other protein A media
- High capacity, low ligand leakage, and high-flow base matrix allow purification of Mabs at process scale
- Fewer regulatory concerns due to the total absence of mammalian culture in the ligand production and purification
- Designed for use with a syringe, a peristaltic pump, or a chromatography system
MabSelect
- Allows at least five times higher flowrates than conventional cross-linked agarose of similar porosity
- Recombinant Protein A ligand promotes specificity of binding to Fc region of IgG; permits one-step purification
- Same recombinant protein A ligand as MabSelect, but with a smaller particle size and greater porosity, for increased dynamic binding capacity
- Allows binding from samples with high expression levels of the monoclonal antibody
- Lowers overall production cost due to the possibility of processing concentrated feedstocks in fewer batches
- Akali-tolerant protein A-derived ligand allows the use of up to 0.5M NaOH for cleaning-in-place (CIP)
- Permits significant cost savings and extension of cycles in regular production
Especificaciones
| Pre-packed Columns | |
| 1.6 cm | |
| <20mL/min. | |
| For fast purification of monoclonal antibodies from large sample volumes, Protein Purification | |
| 5 mL | |
| 4°C to 30°C |
| ∼30 mg/mL Human lgG at 2.4 min. residence time | |
| 0.62 in. | |
| 5 mL | |
| HiTrap MabSelect columns are prepacked with MabSelect, a BioProcess resin for capturing of mAbs from large sample volumes. | |
| 20% Ethanol | |
| 5 Pk. |
Seguridad y manipulación
Nombre del producto
Palabra de advertencia
Clasificación
Indicaciones de peligro
Consejos de prudencia
Otros peligros
- HiTrap MabSelect, 5 ml, 5 x 5 ml
Palabra de advertencia
- Atención
Clasificación
- Líquido inflamable Categoría 3
Indicaciones de peligro
- H226-Líquidos y vapores inflamables.
Consejos de prudencia
- P210-Mantener alejado del calor, de superficies calientes, de chispas, de llamas abiertas y de cualquier otra fuente de ignición. No fumar.
- P241-Utilizar un material eléctrico, de ventilación o de iluminación / / antideflagrante.
- P260-No respirar el polvo/el humo/el gas/la niebla/los vapores/el aerosol.
- P280-Llevar guantes/prendas/gafas/máscara de protección.
- P305+P351+P338-EN CASO DE CONTACTO CON LOS OJOS: Aclarar cuidadosamente con agua durante varios minutos. Quitar las lentes de contacto, si lleva y resulta fácil. Seguir aclarando.
- P501b-Eliminar el contenido/el recipiente en conforme a la reglamentación local/regional/nacional/internacional.
Otros peligros
- MIXTURE LIST-Contém: ethanol
- UNKNOWN ACUTE-16.5% de la mezcla consiste en uno o varios componentes de toxicidad aguda desconocida.