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GDF5 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA597777
Detalles adicionales : Peso : 0.01000kg
Descripción
GDF-5 is expressed in long bones during embryonic development and postnatally in articular cartilage. Mutations in the GDF-5 gene have been implicated in Hunter-Thompson type dwarfism and in Grebe Syndrome, which is characterized by short stature, extra digits, and short and deformed extremities. The mature and functional form of GDF-5 is a homodimer of two 120 amino-acid polypeptide chain (monomers) linked by a single disulfide bond. Each GDF-5 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 27 amino acid signal peptide and a 354 amino acid propeptide. This precursor undergoes intracellular dimerization, and upon secretion it is processed by a furin-type protease.Especificaciones
GDF5 | |
Polyclonal | |
Unconjugated | |
GDF5 | |
BDA1C, Bmp14, BMP-14, Bone morphogenetic protein 14, bp, brachypodism, brp, Cartilage-derived morphogenetic protein 1, cartilage-derived morphogenetic protein-1, CDMP1, Cdmp-1, GDF5, GDF-5, growth differentiation factor 5, growth/differentiation factor 5, H-GDF-5, LAP4, LAP-4, Lipopolysaccharide-associated protein 4, LPS-associated protein 4, OS5, radotermin, SYM1B, SYNS2 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
8200 | |
-20°C or -80°C if preferred | |
Liquid |
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
0.39 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3 | |
P43026 | |
GDF5 | |
Recombinant Human Growth/differentiation factor 5 protein (202-501AA) | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |